Bovilis Guardian vaccine from Merck Animal Health provides broad-spectrum protection against the leading contributors to scours and is the only pregnant cow and heifer vaccine labeled for subcutaneous (SQ) administration. Guardian protects calves from the leading causes of scours including rotavirus, coronavirus, Clostridium perfringens, and E. coli through vaccination of pregnant cows and heifers. Guardian is recommended for use in healthy pregnant heifers and cows 3 months prior to calving as an aid in the prevention of neonatal calf diarrhea caused by enterotoxigenic E. coli pilus type K99, bovine Group A Serotype G6 rotaviruses, enterotoxemia caused by Cl. perfringens Types C and D
Dosage: Inject healthy pregnant cattle with 2 mL subcutaneously 3 months prior to calving. Repeat in 3 - 6 weeks following initial vaccination. For subsequent calving’s, revaccinate with a single 2 mL dose 5 - 7 weeks before calving. For E. coli, protection was shown when the first dose was given as early as 6 months prior to calving