Toxiban Activated Charcoal is active in adsorbing most toxicants except inorganic salts & heavy metals. ToxiBan is the “gold standard” for treating animal poisioning. MedCharTM,activated charcoal, USP, adsorbs toxins in the gastrointestinal tract. Kaolin adds extra adsorbing qualities while protecting the intestinal lining. Sorbitol is a mild hyperosmotic cathartic.
Indications and Usage:
ToxiBan® is most effective when administered as soon as ingestion of a toxicant is suspected. It may be used in some emergencies when absorption of the toxicant is nearly complete or the exposure was via a parenteral route. This latter application usually involves repetitive or multiple doses. Multiple doses may be used to interrupt the enterohepatic circulation of some toxins, thereby preventing their reabsorption.
See package insert for more detailed information.
Contraindications:
There are no known absolute contraindications to the use of activated charcoal. It should not be given simultaneously or shortly before the oral administration of other therapeutic agents such as antibiotics, vitamins or amino acids. Antibiotic therapy should be administered parenterally when ToxiBan is used.
Dosage:
Granules
To make a thin suspension, mix 1 volume measure with 5 to 7 parts cold water (Example: 1 level cup
ToxiBan to 6 cups water). Agitate vigorously for 10 to 30 seconds. For small animals, use 2 to 4
grams per kg (1 to 2 grams per pound) body weight. For large animals, use 0.75 to 2.0 grams per
kilogram (0.35 to 0.9 grams per pound). One pound (453.6 grams) normally treats an animal weighing
225 to 600 kilograms (500 to 1300 pounds).
Administration:
ToxiBan Suspension and Suspension with Sorbitol may be given directly or mixed with a small amount
of cold water to reduce viscosity. For Granule administration, use as a powder in food or dilute to
create a suspension. When a suspension is created, agitate frequently to keep liquid uniform. A
stomach tube is preferred, but an oral drench may be used in emergency.
Precautions:
ToxiBan is an adjunct in the management of poisoning emergencies. Prior to use, proper life support
and gastric empty- ing must be implemented, if indicated. Because more than an hour may pass before
ToxiBan can be administered without regurgitation after an emetic has been given, it may be more
effective to give ToxiBan immediately because adsorption of a toxicant may be a more effective
removal than vomiting.
ToxiBan produces black stools. These stools may have a diarrhea consistency and may persist for
several hours. Sorbitol can create a profound cathartic effect. Proper attention should be provided
to fluid and electrolyte needs to prevent dehydration, possible hypernatremia and even hypotension.
ToxiBan Suspension should be used for multiple use, and cathartics should only be used
intermittently duringmultiple dose activated charcoal use.
Ingredients:
MedChar™ (activated charcoal, USP), Kaolin, and Sorbitol (in granules and suspension with
sorbitol). Suspensions also con- tain suspending agents and preservatives. Granules contain
wetting and dispersing agents.
One pound bottle is adequate in treating a 1200 pound horse or bovine